hrp0084p3-653 | Bone | ESPE2015

Late Sequel of Meningococcemia: Presenting as Skeletal Dysplasia

Karabulut Gulcan Seymen , Yuksel Aysegul Bute , Alanay Yasemin , Hatun Sukru

Background: Although there is considerable literature dealing with the diagnosis, initial management and early complications of meningococcemia, data about late complications is scarce. Growth plates may be influenced permanently by ischemia leading to late orthopedic complications such as leg length discrepancy, angular deformity and distorted body proportion. We present a patient with disproportionate short stature due to late squeal of meningococcemia who was misdiagnosed a...

hrp0086p1-p223 | Diabetes P1 | ESPE2016

The Relationship between the Serum Irisin Levels and the Metabolic Control in adolescents with Type 1 Diabetes

Yuksel Aysegul , Seymen Karabulut Gulcan , Baydemir Canan , Yesiltepe Mutlu Gul , Isgoren Serkan , Cekmen Mustafa , Hatun Sukru

Background: Irisin is an adipomyokine secreted by many tissues. Because it has known relationships with the energy metabolism and exercise, its relationships with obesity and type 2 diabetes (T2D) are being focused on. Its relationship with type 1 diabetes (T1D) is unknown.Objective and hypotheses: In this study, the relationships between the serum irisin level and the metabolic control were investigated in adolescents with T1D.Met...

hrp0082p3-d1-928 | Puberty and Neuroendocrinology | ESPE2014

Characteristics of Children Treated with Leuprolide Acetate

Karabulut Gulcan Seymen , Yuksel Aysegul , Ozsu Elif , Mutlu Gul Yesiltepe , Cizmecioglu Filiz Mine , Hatun Sukru

Objective: This study aims to reveal clinical, hormonal and ultrasound imaging features of patients treated with leuprolide acetate for diagnosis of precoccious puberty.Design: Retrospective analysis of patients with a diagnosis of central precoccious puberty and treated with leuprolide acetate between January 2008 and January 2013.Patients: 81 girls and two boys with early signs of puberty.Results: There was...

hrp0082p3-d3-950 | Puberty and Neuroendocrinology (1) | ESPE2014

Leydig Cell Hyperplasia Mimicking Tumor: a Rare Cause of Isosexual Precoccious Puberty

Karabulut Gulcan Seymen , Hatun Sukru , Yuksel Aysegul , Corapcioglu Funda Ozer , Anik Yonca , Ekingen Gulsen , Gurbuz Yesim

Background: A 5 years and 10 months boy presented with pubic hair, recent penile growth, aggressive behaviour and rapid growth of height. Antenatal, perinatal, and developmental history was unremarkable. There was no family history of precocious puberty. His height and weight were 128 cm (2.24 S.D.) and 25 kg (1.55 S.D.) respectively. Vital signs were normal. He was Tanner 2 for pubic hair and his stretched penis length was 11 cm, right testis vol...